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Refer to Week 7: Social media and citizen science in precision medicine.
1. Over
Refer to Week 7: Social media and citizen science in precision medicine.
1. Over-reporting of a factor (or variable) can influence study results. Give an example of a demographic, lifestyle, or medical factor that might be commonly over-reported by study participants and briefly explain why this may be the case.
2. Citizen science research studies are under way using devices that transmit data via smartphone synchronization and upload to the internet. Choose 5 devices that are generically part of this so-called “internet of things” (IoT) and briefly – in 1-2 sentences – describe how they could be used in a research or clinical trial.
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Refer to Week 8: Counseling skills in precision medicine
1. Your patient is Individual III-4 in this Family History. She comes to you concerned about her family history and wanting to know more about her risk of having children with the disorder running through her family. She tells you that her father (Individual II-3), her male cousin (Individual III-5), and her female cousin’s son (Individual IV-1) all have the same disorder. Based on this family history, please identify the mode of inheritance of the disorder. Explain what characteristics you observe that help identify the pattern. Additionally, to the best of your ability, explain what you would tell her about her risk of having children with this condition?
2. Give your best description of what genetic counseling is and discuss one or two key components of a genetic counseling discussion with a patient who is considering genetic testing.
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Refer to Week 9: The next frontier in healthcare-integrating the microbiome into precision medicine
1. List two primary factors that Bray-Curtis dissimilarity analysis accounts for when comparing the microbial communities.
2. What role does the gut microbiome play in the development of personalized nutrition plans?
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Refer to Week 10-Ethical, Legal, and Social Issues in Precision Medicine
1. Select which of the four principles of bioethics you see as most important in the space of precision medicine. In 1-2 sentences, explain that one principle of bioethics in your own words. Then, present why you think that principle is a key one to focus on in the area of precision medicine.
2. A mother of three has developed ovarian cancer at the age of 33. You suspect she has a germline BRCA mutation and suggest she gets genetic testing. She is hesitant as she is concerned about the impact it will have on her insurance company and any future employers. Briefly explain what protections are in place to protect her genetic data. Are there any gaps in coverage she should be concerned about? Are there any additional considerations she should be concerned about for getting genetic testing?
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